Complications Following Antidotal Use of Intravenous Lipid Emulsion Therapy
نویسندگان
چکیده
منابع مشابه
Review of Intravenous Lipid Emulsion Therapy
Intravenous fat emulsion (IVFE) is an important source of calories and essential fatty acids for patients receiving parenteral nutrition (PN). Administered as an individual infusion or combined with PN, the fats provided by IVFE are vital for cellular structural function and metabolism. The affinity of some medications to lipids has led to the use of IVFE as a treatment for any lipophilic drug ...
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Carbamazepine (CBZ) is a widely prescribed anticonvulsant agent. It is used in treatment of epilepsy including general tonic-clonic, simple partial and complex partial seizures, neuropathicpains, especially in trigeminalneuralgia, central diabetes insipidus, attention-deficit and hyperactivity disorders and bipolar disorders. CBZ overdose is usually associated with cardiac, neurologic and respi...
متن کاملIntravenous lipid emulsion in clinical toxicology
Intravenous lipid emulsion is an established, effective treatment for local anesthetic-induced cardiovascular collapse. The predominant theory for its mechanism of action is that by creating an expanded, intravascular lipid phase, equilibria are established that drive the offending drug from target tissues into the newly formed 'lipid sink'. Based on this hypothesis, lipid emulsion has been con...
متن کاملUse of lipid emulsion therapy in local anesthetic overdose
The use of intravenous lipid emulsion (ILE) therapy as antidote in systemic toxicity of certain agents has gained widespread support. There are increasing data suggesting use of ILE in reversing from local anesthetic-induced systemic toxicity severe, life-threatening cardiotoxicity, although findings are contradictory. Efficiency of ILE was demonstrated in animal studies in the treatment of sev...
متن کاملSystematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity.
BACKGROUND The use of intravenous lipid emulsion (ILE) therapy for the treatment of lipophilic drug toxicity is increasing. Despite this, the evidence for its effect in non-local anesthetic toxicity remains sparse. Furthermore, many case reports describe ILE use for substances in which no clear efficacy data exists. The American Academy of Clinical Toxicology established a lipid emulsion workgr...
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ژورنال
عنوان ژورنال: Journal of Medical Toxicology
سال: 2013
ISSN: 1556-9039,1937-6995
DOI: 10.1007/s13181-013-0356-1